Geniposidic acid upregulates atrial natriuretic peptide secretion and lowers blood pressure in spontaneously hypertensive rats

Geniposidic acid upregulates atrial natriuretic peptide secretion and lowers blood pressure in spontaneously hypertensive rats

Geniposidic acid (GEA), the main ingredient of several medicinal herbs, has pharmacological effects on hypertension, inflammation, diabetes, atherosclerosis, and cancer. The current study evaluated the mechanism underlying the hypotensive effects of a single oral administration of 100 mg GEA/kg in m...

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Bibliographic Details
Main Authors: Kozo Nakamura, Shingo Hosoo, Shohei Yamaguchi, Masahiro Koyama, Ryo Yamazaki, Tetsuya Hirata, Yasuyo Yamaguchi, Hiroo Yamasaki, Naoto Minamino, Keiji Wada, Sansei Nishibe
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Functional Foods
Subjects:
Geniposidic acid
Spontaneously hypertensive rats
Atrial natriuretic peptide
Glucagon-like peptide-1
Tochu-cha
Cardioprotection
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617306473

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http://www.sciencedirect.com/science/article/pii/S1756464617306473

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