Bevacizumab attenuates hepatic fibrosis in rats by inhibiting activation of hepatic stellate cells.

Angiogenesis is a fundamental part of the response to tissue injury, which is involved in the development of hepatic fibrosis. Vascular endothelial growth factor plays an important role in angiogenesis. The expression of VEGF is increased during hepatic fibrogenesis and correlates with the micro-ves...

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Bibliographic Details
Main Authors: Yangqing Huang, Helin Feng, Tong Kan, Bin Huang, Minfeng Zhang, Yesheng Li, Changying Shi, Mengchao Wu, Yunquan Luo, Jiamei Yang, Feng Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3758295?pdf=render