Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain

Rapid changes in tissue mechanics regulate cell behaviour in the developing embryonic brain

Tissue mechanics is important for development; however, the spatio-temporal dynamics of in vivo tissue stiffness is still poorly understood. We here developed tiv-AFM, combining time-lapse in vivo atomic force microscopy with upright fluorescence imaging of embryonic tissue, to show that during deve...

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Bibliographic Details
Main Authors: Amelia J Thompson, Eva K Pillai, Ivan B Dimov, Sarah K Foster, Christine E Holt, Kristian Franze
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-01-01
Series:eLife
Subjects:
atomic force microscopy
mechanics
stiffness
mechanotransduction
durotaxis
axon guidance
Online Access:https://elifesciences.org/articles/39356

Internet

https://elifesciences.org/articles/39356

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