Identification and characterization of proteins of unknown function (PUFs) in Clostridium thermocellum DSM 1313 strains as potential genetic engineering targets

Abstract Background Mass spectrometry-based proteomics can identify and quantify thousands of proteins from individual microbial species, but a significant percentage of these proteins are unannotated and hence classified as proteins of unknown function (PUFs). Due to the difficulty in extracting me...

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Bibliographic Details
Main Authors: Suresh Poudel, Alexander L. Cope, Kaela B. O’Dell, Adam M. Guss, Hyeongmin Seo, Cong T. Trinh, Robert L. Hettich
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Biotechnology for Biofuels
Online Access:https://doi.org/10.1186/s13068-021-01964-4