Docosahexaenoic Acid Reduces the Incidence of Early Afterdepolarizations caused by Oxidative Stress in Rabbit Ventricular Myocytes

Docosahexaenoic Acid Reduces the Incidence of Early Afterdepolarizations caused by Oxidative Stress in Rabbit Ventricular Myocytes

Accumulating evidence has suggested that ω3-polyunsaturated fatty acids (ω3-PUFAs) may have beneficial effects in the prevention/treatment of cardiovascular diseases, while controversies still remain regarding their antiarrhythmic potential. It is not clear yet whether ω-3 PUFAs can suppress early...

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Bibliographic Details
Main Authors: Zhenghang eZhao, Hairuo eWen, Nadezhda eFefelova, Charelle eAllen, Nancy eGuillaume, Dandan eXiao, Chen eHuang, Wei-Jin eZang, Judith K Gwathmey, Lai-Hua eXie
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Physiology
Subjects:
Reactive Oxygen Species
Sodium channel
docosahexaenoic acid
early afterdepolarization
H2O2
L-type calcium channel
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00252/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00252/full

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