Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936

Plasma levels of neurological proteins have the potential to serve as biomarkers for neurological conditions. Here, Hillary et al. perform genome- and epigenome-wide association studies for 92 neurological proteins and identify 41 genomic loci for 33 proteins and 26 CpG sites for 9 proteins.

Bibliographic Details
Main Authors: Robert F. Hillary, Daniel L. McCartney, Sarah E. Harris, Anna J. Stevenson, Anne Seeboth, Qian Zhang, David C. Liewald, Kathryn L. Evans, Craig W. Ritchie, Elliot M. Tucker-Drob, Naomi R. Wray, Allan F. McRae, Peter M. Visscher, Ian J. Deary, Riccardo E. Marioni
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11177-x