Age, lipofuscin and melanin oxidation affect fundus near-infrared autofluorescence

Background: Fundus autofluorescence is a non-invasive imaging technique in ophthalmology. Conventionally, short-wavelength autofluorescence (SW-AF) is used for detection of lipofuscin, a byproduct of the visual cycle which accumulates with age or disease in the retinal pigment epithelium (RPE). Furt...

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Bibliographic Details
Main Authors: Tatjana Taubitz, Yuan Fang, Antje Biesemeier, Sylvie Julien-Schraermeyer, Ulrich Schraermeyer
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641930636X