Synthesis and docking study on thiadiazolo[3,2-a][1,3]diazepin-8(5H)-one derivatives as selective GABA(A) agonists
HIE-124 is a new member of ultra-short acting hypnotics’ drug family. In this research, the synthesis of analogues of HIE-124 drug in the heterocyclic thiazole ring replaced to thiadiazole, will be presented. Thiadiazolodiazepines during a two-step reaction starting from the amino thiadiaz...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Islamic Azad University
2016-09-01
|
| Series: | Journal of Pharmaceutical and Health Sciences |
| Subjects: | |
| Online Access: | http://www.jphs.ir/article_527123.html |