Novel Molecular Targets for the Treatment of Gastroenteropancreatic Endocrine Tumors: Answers and Unsolved Problems

Novel Molecular Targets for the Treatment of Gastroenteropancreatic Endocrine Tumors: Answers and Unsolved Problems

As more knowledge on molecular alterations favoring carcinogenesis and spreading of gastroenteropancreatic endocrine tumors has become available, a number of targeted agents interfering with key growth and angiogenic pathways have been explored in preclinical and clinical studies. The mTOR inhibitor...

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Bibliographic Details
Main Authors: Gianfranco Delle Fave, Detlef K. Bartsch, Francesco Panzuto, Maria Rinzivillo, Volker Fendrich, Gabriele Capurso
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:International Journal of Molecular Sciences
Subjects:
gastroenteropancreatic endocrine tumors
target therapy
mTOR
angiogenesis
Src
hedgehog
combined treatment
resistance
Online Access:http://www.mdpi.com/1422-0067/14/1/30

Internet

http://www.mdpi.com/1422-0067/14/1/30

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