The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis

The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis

The cell wall of Mycobacterium tuberculosis is composed of unique lipids that are important for pathogenesis. Indeed, the first-ever genetic screen in M. tuberculosis identified genes involved in the biosynthesis and transport of the cell wall lipid PDIM (phthiocerol dimycocerosates) as crucial for...

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Bibliographic Details
Main Authors: Jeff Quigley, V. Keith Hughitt, Carlos A. Velikovsky, Roy A. Mariuzza, Najib M. El-Sayed, Volker Briken, Stefan H. E. Kaufmann
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/2/e00148-17

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http://mbio.asm.org/cgi/content/full/8/2/e00148-17

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