Prognostic value of PLAGL1-specific CpG site methylation in soft-tissue sarcomas.

Prognostic value of PLAGL1-specific CpG site methylation in soft-tissue sarcomas.

Soft tissue sarcomas (STS) are rare, complex tumors with a poor prognosis. The identification of new prognostic biomarkers is needed to improve patient management. Our aim was to determine the methylation status of the 118 CpG sites in the PLAGL1 tumor-suppressor gene P1 CpG island promoter and stud...

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Bibliographic Details
Main Authors: Anne-Lise Peille, Veronique Brouste, Audrey Kauffmann, Pauline Lagarde, Valerie Le Morvan, Jean-Michel Coindre, Frederic Chibon, Laurence Bresson-Bepoldin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3829972?pdf=render

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http://europepmc.org/articles/PMC3829972?pdf=render

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