Methyl Salicylate Lactoside Protects Neurons Ameliorating Cognitive Disorder Through Inhibiting Amyloid Beta-Induced Neuroinflammatory Response in Alzheimer’s Disease

Methyl Salicylate Lactoside Protects Neurons Ameliorating Cognitive Disorder Through Inhibiting Amyloid Beta-Induced Neuroinflammatory Response in Alzheimer’s Disease

Neuroinflammatory reactions mediated by microglia and astrocytes have been shown to play a key role in early progression of Alzheimer’s disease (AD). Increased evidences have demonstrated that neurons exacerbate local inflammatory reactions by producing inflammatory mediators and act as an important...

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Bibliographic Details
Main Authors: Jinze Li, Xiaowei Ma, Yu Wang, Chengjuan Chen, Min Hu, Linlin Wang, Junmin Fu, Gaona Shi, Dongming Zhang, Tiantai Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
cyclooxygenase
methyl salicylate lactoside
mitogen-activated protein kinase
neuroinflammation
neuron
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00085/full

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http://journal.frontiersin.org/article/10.3389/fnagi.2018.00085/full

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