A LINE-1 insertion situated in the promoter of IMPG2 is associated with autosomal recessive progressive retinal atrophy in Lhasa Apso dogs

A LINE-1 insertion situated in the promoter of IMPG2 is associated with autosomal recessive progressive retinal atrophy in Lhasa Apso dogs

Abstract Background Canine progressive retinal atrophies are a group of hereditary retinal degenerations in dogs characterised by depletion of photoreceptor cells in the retina, which ultimately leads to blindness. PRA in the Lhasa Apso (LA) dog has not previously been clinically characterised or de...

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Bibliographic Details
Main Authors: Rebekkah J. Hitti-Malin, Louise M. Burmeister, Sally L. Ricketts, Thomas W. Lewis, Louise Pettitt, Mike Boursnell, Ellen C. Schofield, David Sargan, Cathryn S. Mellersh
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Genetics
Subjects:
Canine
Dog
Progressive retinal atrophy
PRA
Canine retinal degeneration
Inherited
Online Access:http://link.springer.com/article/10.1186/s12863-020-00911-w

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http://link.springer.com/article/10.1186/s12863-020-00911-w

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