Streptococcus pneumoniae endopeptidase O (PepO) elicits a strong innate immune response in mice via TLR2 and TLR4 signaling pathways

Streptococcus pneumoniae endopeptidase O (PepO) elicits a strong innate immune response in mice via TLR2 and TLR4 signaling pathways

Interaction between virulence factors of streptococcus pneumoniae and innate immune receptors elicits host responses through specific signaling pathways during infection. Insights into the signaling events may provide a better knowledge of the starting events for host-pathogen interaction. Here we d...

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Bibliographic Details
Main Authors: Hong eZhang, Li hua Kang, Hua eYao, Yu juan He, Xiao fang Wang, Wen chun Xu, Zhi xin Song, Yi bing Yin, Xue Mei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Signaling Pathways
TLR2;
TLR4;
Innate immunity;
Streptococcus pneumoniae;
PepO;
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00023/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00023/full

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