A web tool for designing and conducting phase I trials using the continual reassessment method
Abstract Background Broad implementation of model-based dose-finding methods, such as the continual reassessment method (CRM), has been limited, with traditional or modified 3 + 3 designs remaining in frequent use. Part of the reason is the lack of reliable, easy-to-use, and robust software tools fo...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-02-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12885-018-4038-x |