Standardization of the teratoma assay for analysis of pluripotency of human ES cells and biosafety of their differentiated progeny.

Standardization of the teratoma assay for analysis of pluripotency of human ES cells and biosafety of their differentiated progeny.

Teratoma tumor formation is an essential criterion in determining the pluripotency of human pluripotent stem cells. However, currently there is no consistent protocol for assessment of teratoma forming ability. Here we present detailed characterization of a teratoma assay that is based on subcutaneo...

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Bibliographic Details
Main Authors: Michal Gropp, Vitali Shilo, Gilad Vainer, Miri Gov, Yaniv Gil, Hanita Khaner, Limor Matzrafi, Maria Idelson, Juri Kopolovic, Naomi B Zak, Benjamin E Reubinoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3458078?pdf=render

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http://europepmc.org/articles/PMC3458078?pdf=render

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