A potent human neutralizing antibody Fc-dependently reduces established HBV infections

A potent human neutralizing antibody Fc-dependently reduces established HBV infections

Hepatitis B virus (HBV) infection is a major global health problem. Currently-available therapies are ineffective in curing chronic HBV infection. HBV and its satellite hepatitis D virus (HDV) infect hepatocytes via binding of the preS1 domain of its large envelope protein to sodium taurocholate cot...

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Bibliographic Details
Main Authors: Dan Li, Wenhui He, Ximing Liu, Sanduo Zheng, Yonghe Qi, Huiyu Li, Fengfeng Mao, Juan Liu, Yinyan Sun, Lijing Pan, Kaixin Du, Keqiong Ye, Wenhui Li, Jianhua Sui
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
HBV
NTCP
preS1
antibody
Fc receptor
effector function
Online Access:https://elifesciences.org/articles/26738

Internet

https://elifesciences.org/articles/26738

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