Multifaceted Regulation of PTEN Subcellular Distributions and Biological Functions
Phosphatase and tensin homolog deleted on chromosome 10 (<i>PTEN</i>) is a tumor suppressor gene frequently found to be inactivated in over 30% of human cancers. <i>PTEN</i> encodes a 54-kDa lipid phosphatase that serves as a gatekeeper of the phosphoinositide 3-kinase pathwa...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-08-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/11/9/1247 |