What Do We Learn from Spheroid Culture Systems? Insights from Tumorspheres Derived from Primary Colon Cancer Tissue.

Due to their self-renewal and tumorigenic properties, tumor-initiating cells (TICs) have been hypothesized to be important targets for colorectal cancer (CRC). However the study of TICs is hampered by the fact that the identification and culturing of TICs is still a subject of extensive debate. Floa...

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Bibliographic Details
Main Authors: Komal Qureshi-Baig, Pit Ullmann, Fabien Rodriguez, Sónia Frasquilho, Petr V Nazarov, Serge Haan, Elisabeth Letellier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4706382?pdf=render