Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra

<p>Abstract</p> <p>Background</p> <p>Recent attention has focused on understanding the role of the brain-renin-angiotensin-system (RAS) in stroke and neurodegenerative diseases. Direct evidence of a role for the brain-RAS in Parkinson's disease (PD) comes from stud...

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Bibliographic Details
Main Authors: Jhaveri Vimal V, Skoch Jesse, Snell Lawrence D, Hoover Brian R, Ahmadi Ferogh A, Jones Susan M, Grammatopoulos Tom N, Poczobutt Andy M, Weyhenmeyer James A, Zawada W Michael
Format: Article
Language:English
Published: BMC 2007-01-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/2/1/1