Comparative analysis of ChIP-exo peak-callers: impact of data quality, read duplication and binding subtypes
Abstract Background ChIP (Chromatin immunoprecipitation)-exo has emerged as an important and versatile improvement over conventional ChIP-seq as it reduces the level of noise, maps the transcription factor (TF) binding location in a very precise manner, upto single base-pair resolution, and enables...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-02-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-020-3403-3 |