Comparative analysis of ChIP-exo peak-callers: impact of data quality, read duplication and binding subtypes

Abstract Background ChIP (Chromatin immunoprecipitation)-exo has emerged as an important and versatile improvement over conventional ChIP-seq as it reduces the level of noise, maps the transcription factor (TF) binding location in a very precise manner, upto single base-pair resolution, and enables...

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Bibliographic Details
Main Authors: Vasudha Sharma, Sharmistha Majumdar
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-3403-3