Low dose oral beta-lactamase protects the gut microbiome from oral beta-lactam-mediated damage in dogs

Antibiotics, while lifesaving, damage the gut microbiome and can precipitate proliferation of pathobionts. A strategy to preserve gut microbiome integrity is to eliminate biologically active antimicrobials excreted into the gastrointestinal tract (GI) without negatively affecting antibiotic therapeu...

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Bibliographic Details
Main Authors: Sheila Connelly, Brian Fanelli, Nur A. Hasan, Rita R. Colwell, Michael Kaleko
Format: Article
Language:English
Published: AIMS Press 2019-11-01
Series:AIMS Public Health
Subjects:
Online Access:https://www.aimspress.com/article/10.3934/publichealth.2019.4.477/fulltext.html