Dengue-2 and yellow fever 17DD viruses infect human dendritic cells, resulting in an induction of activation markers, cytokines and chemokines and secretion of different TNF-α and IFN-α profiles

Dengue-2 and yellow fever 17DD viruses infect human dendritic cells, resulting in an induction of activation markers, cytokines and chemokines and secretion of different TNF-α and IFN-α profiles

Flaviviruses cause severe acute febrile and haemorrhagic infections, including dengue and yellow fever and the pathogenesis of these infections is caused by an exacerbated immune response. Dendritic cells (DCs) are targets for dengue virus (DENV) and yellow fever virus (YF) replication and are the f...

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Bibliographic Details
Main Authors: Mariana Gandini, Sonia Regina Nogueira Ignacio Reis, Amanda Torrentes-Carvalho, Elzinandes Leal Azeredo, Marcos da Silva Freire, Ricardo Galler, Claire Fernandes Kubelka
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2011-08-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
cytokines
dendritic cells
dengue virus
yellow fever vaccine
flavivirus
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000500012&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000500012&lng=en&tlng=en

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