Population Pharmacokinetics and Dose Optimization of Ganciclovir in Critically Ill Children

Objective: The present study aims to establish a population pharmacokinetic model of ganciclovir and optimize the dosing regimen in critically ill children suffering from cytomegalovirus related disease.Methods: A total of 104 children were included in the study. The population pharmacokinetic model...

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Bibliographic Details
Main Authors: SiChan Li, Chang Shu, SanLan Wu, Hua Xu, Yang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.614164/full