Effect of adenovirus infection on transgene expression under the adenoviral MLP/TPL and the CMVie promoter/enhancer in CHO cells

Effect of adenovirus infection on transgene expression under the adenoviral MLP/TPL and the CMVie promoter/enhancer in CHO cells

The adenovirus major late promoter (MLP) and its translational regulator – the tripartite leader (TPL) sequence – can actively drive efficient gene expression during adenoviral infection. However, both elements have not been widely tested in transgene expression outside of the adenovirus genome cont...

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Bibliographic Details
Main Authors: Mohamed A. El-Mogy, Moemen A.K. Abdalla, Vanja Misic, Yousef Haj-Ahmad
Format: Article
Language:English
Published: SpringerOpen 2017-06-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Transgene expression
Adenovirus
MLP
TPL
CMVie promoter/enhancer
Online Access:http://www.sciencedirect.com/science/article/pii/S1687157X17300215

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http://www.sciencedirect.com/science/article/pii/S1687157X17300215

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