Enteropathogenic Escherichia coli Infection Induces Diarrhea, Intestinal Damage, Metabolic Alterations, and Increased Intestinal Permeability in a Murine Model

Enteropathogenic Escherichia coli Infection Induces Diarrhea, Intestinal Damage, Metabolic Alterations, and Increased Intestinal Permeability in a Murine Model

Enteropathogenic E. coli (EPEC) are recognized as one of the leading bacterial causes of infantile diarrhea worldwide. Weaned C57BL/6 mice pretreated with antibiotics were challenged orally with wild-type EPEC or escN mutant (lacking type 3 secretion system) to determine colonization, inflammatory r...

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Bibliographic Details
Main Authors: Solanka E. Ledwaba, Deiziane V. S. Costa, David T. Bolick, Natasa Giallourou, Pedro H. Q. S. Medeiros, Jonathan R. Swann, Afsatou N. Traore, Natasha Potgieter, James P. Nataro, Richard L. Guerrant
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
enteropathogenic Escherichia coli
murine model
diarrhea
enteropathy
antibiotics
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.595266/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2020.595266/full

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