Production of homozygous klotho knockout porcine embryos cloned from genome-edited porcine fibroblasts
Even though klotho deficiency in mice exhibits multiple aging-like phenotypes, studies using large animal models such as pigs, which have many similarities to humans, have been limited due to the absence of cell lines or animal models. The objective of this study was to generate homozygous klotho kn...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Korean Society of Animal Reproduction and Biotechnology
2016-09-01
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Series: | Journal of Animal Reproduction and Biotechnology |
Subjects: | |
Online Access: | http://www.e-jarb.org/journal/view.html?uid=1526&vmd=Full |