Piwi genes are dispensable for normal hematopoiesis in mice.

Hematopoietic stem cells (HSC) must engage in a life-long balance between self-renewal and differentiation to sustain hematopoiesis. The highly conserved PIWI protein family regulates proliferative states of stem cells and their progeny in diverse organisms. A Human piwi gene (for clarity, the non-i...

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Bibliographic Details
Main Authors: Mona J Nolde, Ee-Chun Cheng, Shangqin Guo, Haifan Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3751959?pdf=render