Environmental enrichment alters protein expression as well as the proteomic response to cocaine in rat nucleus accumbens

Environmental enrichment alters protein expression as well as the proteomic response to cocaine in rat nucleus accumbens

Prior research demonstrated that environmental enrichment creates individual differences in behavior leading to a protective addiction phenotype in rats. Understanding the mechanisms underlying this phenotype will guide selection of targets for much-needed novel pharmacotherapeutics. The current stu...

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Bibliographic Details
Main Authors: Cheryl F. Lichti, Xiuzhen eFan, Robert D. English, Yafang eZhang, Dingge eLi, Fanping eKong, Mala eSinha, Clark R. Andersen, Heidi eSpratt, Bruce A. Luxon, Thomas A. Green
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Cocaine
Proteomics
drug addiction
Drug abuse
Differential rearing
label-free quantification
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00246/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00246/full

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