Immobilization of homogeneous monomeric, oligomeric and fibrillar Aβ species for reliable SPR measurements.

Immobilization of homogeneous monomeric, oligomeric and fibrillar Aβ species for reliable SPR measurements.

There is strong evidence that the amyloid-beta peptide (Aβ) plays a central role in the pathogenesis of Alzheimer's disease (AD). In this context, a detailed quantitative description of the interactions with different Aβ species is essential for characterization of physiological and artificial...

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Bibliographic Details
Main Authors: Daniel Frenzel, Julian M Glück, Oleksandr Brener, Filipp Oesterhelt, Luitgard Nagel-Steger, Dieter Willbold
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3940443?pdf=render

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http://europepmc.org/articles/PMC3940443?pdf=render

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