IL-23 signaling regulation of pro-inflammatory T-cell migration uncovered by phosphoproteomics.
Interleukin 23 (IL-23) triggers pathogenic features in pro-inflammatory, IL-17-secreting T cells (Th17 and Tγδ17) that play a key role in the development of inflammatory diseases. However, the IL-23 signaling cascade remains largely undefined. Here, we used quantitative phosphoproteomics to characte...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-03-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3000646 |