IL-23 signaling regulation of pro-inflammatory T-cell migration uncovered by phosphoproteomics.

Interleukin 23 (IL-23) triggers pathogenic features in pro-inflammatory, IL-17-secreting T cells (Th17 and Tγδ17) that play a key role in the development of inflammatory diseases. However, the IL-23 signaling cascade remains largely undefined. Here, we used quantitative phosphoproteomics to characte...

Full description

Bibliographic Details
Main Authors: Candelas Álvarez-Salamero, Raquel Castillo-González, Gloria Pastor-Fernández, Isabel R Mariblanca, Jesús Pino, Danay Cibrian, María N Navarro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000646