Chaperonin Abundance Enhances Bacterial Fitness

Chaperonin Abundance Enhances Bacterial Fitness

The ability of chaperonins to buffer mutations that affect protein folding pathways suggests that their abundance should be evolutionarily advantageous. Here, we investigate the effect of chaperonin overproduction on cellular fitness in Escherichia coli. We demonstrate that chaperonin abundance conf...

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Bibliographic Details
Main Authors: C. M. Santosh Kumar, Kritika Chugh, Anirban Dutta, Vishnuvardhan Mahamkali, Tungadri Bose, Sharmila S. Mande, Shekhar C. Mande, Peter A. Lund
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
metabolic flux
GroEL
evolution
proteomics
metabolism
competitive index
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.669996/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.669996/full

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