Hyperhomocysteinemia and MTHFR Polymorphisms as Antenatal Risk Factors of White Matter Abnormalities in Two Cohorts of Late Preterm and Full Term Newborns

Hyperhomocysteinemia and MTHFR Polymorphisms as Antenatal Risk Factors of White Matter Abnormalities in Two Cohorts of Late Preterm and Full Term Newborns

Higher total homocysteine (tHcy) levels, and C677T and A1298C methylenetetrahydrofolate (MTHFR) polymorphisms, have been reported in preterm or full term newborns with neonatal encephalopathy following perinatal hypoxic-ischemic insult. This study investigated the causal role of tHcy and MTHFR polym...

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Main Authors: Lucia M. Marseglia, Antonio Nicotera, Vincenzo Salpietro, Elisa Giaimo, Giovanna Cardile, Maria Bonsignore, Angela Alibrandi, Daniela Caccamo, Sara Manti, Gabriella D’Angelo, Carmelo Mamì, Gabriella Di Rosa
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2015/543134

Internet

http://dx.doi.org/10.1155/2015/543134

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