Gephyrin, the enigmatic organizer at GABAergic synapses

Gephyrin, the enigmatic organizer at GABAergic synapses

GABAA receptors are clustered at synaptic sites to achieve a high density of postsynaptic receptors opposite the input axonal terminals. This allows an efficient propagation of GABA mediated signals, which mostly result in neuronal inhibition. A key organizer for inhibitory synaptic receptors is the...

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Bibliographic Details
Main Authors: Verena Eva Tretter, Jayanta eMukherjee, Hans Michael Maric, Hermann eSchindelin, Werner eSieghart, Stephen J. Moss
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
GABAA receptors
gephyrin
receptor clustering
synapse formation
inhibitory synapse
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2012.00023/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2012.00023/full

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