From inflammation to gastric cancer – the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases

From inflammation to gastric cancer – the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases

Abstract Infections with the human pathogen Helicobacter pylori (H. pylori) are closely associated with the development of inflammatory disorders and neoplastic transformation of the gastric epithelium. Drastic changes in the micromilieu involve a complex network of H. pylori-regulated signal transd...

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Bibliographic Details
Main Authors: Silja Wessler, Linda M. Krisch, Dominik P. Elmer, Fritz Aberger
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Cell Communication and Signaling
Subjects:
Helicobacter pylori
Gastric cancer
Hedgehog/GLI signaling
Tumor microenvironment
Online Access:http://link.springer.com/article/10.1186/s12964-017-0171-4

Internet

http://link.springer.com/article/10.1186/s12964-017-0171-4

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