Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways

Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways

Background and purpose: Tannic acid (TA), a group of polyphenolic compounds, has multiple anticancer, antimutagenic, antioxidant and anti-inflammatory activities. However, the effects of TA on arsenic trioxide (ATO)-induced nephrotoxicity are still relatively unknown. This study investigated the pro...

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Bibliographic Details
Main Authors: Weiyue Jin, Yurun Xue, Yucong Xue, Xue Han, Qiongtao Song, Jianping Zhang, Ziliang Li, Jie Cheng, Shengjiang Guan, Shijiang Sun, Li Chu
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Tannic acid
Arsenic trioxide
Nephrotoxicity
NF-κB
Nrf2
TNF-α
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220302389

Internet

http://www.sciencedirect.com/science/article/pii/S0753332220302389

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