RNAseq Analysis of Rodent Spaceflight Experiments Is Confounded by Sample Collection Techniques

Summary: To understand the physiological changes that occur in response to spaceflight, mice are transported to the International Space Station (ISS) and housed for variable periods of time before euthanasia on-orbit or return to Earth. Sample collection under such difficult conditions introduces co...

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Bibliographic Details
Main Authors: San-Huei Lai Polo, Amanda M. Saravia-Butler, Valery Boyko, Marie T. Dinh, Yi-Chun Chen, Homer Fogle, Sigrid S. Reinsch, Shayoni Ray, Kaushik Chakravarty, Oana Marcu, Rick B. Chen, Sylvain V. Costes, Jonathan M. Galazka
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220309305