Cathepsin L Promotes Vascular Intimal Hyperplasia after Arterial Injury

Cathepsin L Promotes Vascular Intimal Hyperplasia after Arterial Injury

Abstract The inflammatory pathways that drive the development of intimai hyperplasia (IH) following arterial injury are not fully understood. We hypothesized that the lysosomal cysteine protease cathepsin L activates processes leading to IH after arterial injury. Using a mouse model of wire-induced...

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Bibliographic Details
Main Authors: Jingjing Cai, Hua Zhong, Jinze Wu, Rui-Fang Chen, Huan Yang, Yousef Al-Abed, Ying Li, Xiaohui Li, Weihong Jiang, Marcelo F. Montenegro, Hong Yuan, Timothy R. Billiar, Alex F. Chen
Format: Article
Language:English
Published: BMC 2017-03-01
Series:Molecular Medicine
Online Access:http://link.springer.com/article/10.2119/molmed.2016.00222

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http://link.springer.com/article/10.2119/molmed.2016.00222

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