Inhibiting eukaryotic ribosome biogenesis

Inhibiting eukaryotic ribosome biogenesis

Abstract Background Ribosome biogenesis is a central process in every growing cell. In eukaryotes, it requires more than 250 non-ribosomal assembly factors, most of which are essential. Despite this large repertoire of potential targets, only very few chemical inhibitors of ribosome biogenesis are k...

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Bibliographic Details
Main Authors: Dominik Awad, Michael Prattes, Lisa Kofler, Ingrid Rössler, Mathias Loibl, Melanie Pertl, Gertrude Zisser, Heimo Wolinski, Brigitte Pertschy, Helmut Bergler
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Biology
Online Access:http://link.springer.com/article/10.1186/s12915-019-0664-2

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http://link.springer.com/article/10.1186/s12915-019-0664-2

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