Ocular surface ectoderm instigated by WNT inhibition and BMP4

Ocular surface ectoderm instigated by WNT inhibition and BMP4

We sought to elucidate how and when the ocular surface ectoderm commits to its differentiation into the corneal epithelium in eye development from human induced pluripotent stem cells (hiPSCs) under the influence of WNT signaling and the actions of BMP4. These signals are key drivers ocular surface...

Full description

Bibliographic Details
Main Authors: Yuki Kobayashi, Ryuhei Hayashi, Shun Shibata, Andrew J. Quantock, Kohji Nishida
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Stem Cell Research
Subjects:
Human iPS cells
Ocular surface ectoderm
Epithelial stem cells
Corneal epithelium
WNT signaling
BMP4
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120301690

Internet

http://www.sciencedirect.com/science/article/pii/S1873506120301690

Similar Items