Structural elements that govern Sec14-like PITP sensitivities to potent small molecule inhibitors[S]

Structural elements that govern Sec14-like PITP sensitivities to potent small molecule inhibitors[S]

Sec14-like phosphatidylinositol transfer proteins (PITPs) play important biological functions in integrating multiple aspects of intracellular lipid metabolism with phosphatidylinositol-4-phosphate signaling. As such, these proteins offer new opportunities for highly selective chemical interference...

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Bibliographic Details
Main Authors: Danish Khan, Kaitlyn R. McGrath, Oleksandra Dorosheva, Vytas A. Bankaitis, Ashutosh Tripathi
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Journal of Lipid Research
Subjects:
lipid signaling
lipid transfer proteins
phospholipids
phosphatidylinositol transfer protein
phosphatidylcholine
phosphoinositides
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520354201

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http://www.sciencedirect.com/science/article/pii/S0022227520354201

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