The Ebola-Glycoprotein Modulates the Function of Natural Killer Cells

The Ebola-Glycoprotein Modulates the Function of Natural Killer Cells

The Ebola virus (EBOV) uses evasion mechanisms that directly interfere with host T-cell antiviral responses. By steric shielding of human leukocyte antigen class-1, the Ebola glycoprotein (GP) blocks interaction with T-cell receptors (TCRs), thus rendering T cells unable to attack virus-infected cel...

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Bibliographic Details
Main Authors: Avishay Edri, Avishai Shemesh, Muhammed Iraqi, Omri Matalon, Michael Brusilovsky, Uzi Hadad, Olga Radinsky, Orly Gershoni-Yahalom, John M. Dye, Ofer Mandelboim, Mira Barda-Saad, Leslie Lobel, Angel Porgador
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
Ebola GP
Ebola
modulation of immune system
viral evasion strategies
NKG2D
MICA
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01428/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01428/full

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