Locus-specific hypomethylation of the mouse IAP retrotransposon is associated with transcription factor-binding sites

Abstract Background Intracisternal A particle (IAP) is one of the most transpositionally active retrotransposons in the mouse genome, but its expression varies between cell types. This variation is believed to arise from differences in the epigenetic state (e.g., DNA methylation) of the 5′ long term...

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Bibliographic Details
Main Authors: Ken-ichi Shimosuga, Kei Fukuda, Hiroyuki Sasaki, Kenji Ichiyanagi
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Mobile DNA
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13100-017-0105-0