Evolution combined with genomic study elucidates genetic bases of isobutanol tolerance in <it>Escherichia coli</it>

<p>Abstract</p> <p>Background</p> <p>Isobutanol is a promising next-generation biofuel with demonstrated high yield microbial production, but the toxicity of this molecule reduces fermentation volumetric productivity and final titer. Organic solvent tolerance is a compl...

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Bibliographic Details
Main Authors: Schwartz Donald R, Ward Rebecca J, McConnell Catie A, Xie Bin, Veloso Artur B, Zaroff Ted A, Chen Yu, Lin Fengming, Lesnefsky Ann A, Minty Jeremy J, Rouillard Jean-Marie, Gao Yuan, Gulari Erdogan, Lin Xiaoxia
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/10/1/18