The Effect of 42-Day Exposure to a Low Deoxynivalenol Dose on the Immunohistochemical Expression of Intestinal ERs and the Activation of CYP1A1 and GSTP1 Genes in the Large Intestine of Pre-pubertal Gilts

The Effect of 42-Day Exposure to a Low Deoxynivalenol Dose on the Immunohistochemical Expression of Intestinal ERs and the Activation of CYP1A1 and GSTP1 Genes in the Large Intestine of Pre-pubertal Gilts

Deoxynivalenol (DON) is a mycotoxin that contaminates various plant materials. Exposure to DON can disrupt hormonal homeostasis, decrease body weight gains and modulate the immune system in pigs. It can also cause diarrhea, vomiting, leukocytosis, hemorrhaging or even death. Prolonged exposure to lo...

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Bibliographic Details
Main Authors: Magdalena Gajęcka, Paweł Brzuzan, Iwona Otrocka-Domagała, Łukasz Zielonka, Sylwia Lisieska-Żołnierczyk, Maciej T. Gajęcki
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Veterinary Science
Subjects:
deoxynivalenol
intestines
ERα and ERβ immunohistochemistry
colon
activation of CYP1A1 and GSTP1 genes
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.644549/full

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https://www.frontiersin.org/articles/10.3389/fvets.2021.644549/full

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