Slc20a2-Deficient Mice Exhibit Multisystem Abnormalities and Impaired Spatial Learning Memory and Sensorimotor Gating but Normal Motor Coordination Abilities

Slc20a2-Deficient Mice Exhibit Multisystem Abnormalities and Impaired Spatial Learning Memory and Sensorimotor Gating but Normal Motor Coordination Abilities

BackgroundPrimary familial brain calcification (PFBC, OMIM#213600), also known as Fahr’s disease, is a rare autosomal dominant or recessive neurodegenerative disorder characterized by bilateral and symmetrical microvascular calcifications affecting multiple brain regions, particularly the basal gang...

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Bibliographic Details
Main Authors: Yaqiong Ren, Yuqi Shen, Nuo Si, Shiqi Fan, Yi Zhang, Wanhai Xu, Lei Shi, Xue Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Genetics
Subjects:
primary familial brain calcification
PFBC
Slc20a2
vascular calcification
cognitive
sensorimotor gating
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.639935/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.639935/full

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