Characteristics and Immunomodulating Functions of Adipose-Derived and Bone Marrow-Derived Mesenchymal Stem Cells Across Defined Human Leukocyte Antigen Barriers

Characteristics and Immunomodulating Functions of Adipose-Derived and Bone Marrow-Derived Mesenchymal Stem Cells Across Defined Human Leukocyte Antigen Barriers

BackgroundVascularized composite allotransplantation opens new possibilities in reconstructive transplantation such as hand or face transplants. Lifelong immunosuppression and its side-effects are the main drawbacks of this procedure. Mesenchymal stem cells (MSCs) have clinically useful immunomodula...

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Bibliographic Details
Main Authors: Matthias Waldner, Wensheng Zhang, Isaac B. James, Kassandra Allbright, Emmanuelle Havis, Jacqueline M. Bliley, Aurora Almadori, Riccardo Schweizer, Jan A. Plock, Kia M. Washington, Vijay S. Gorantla, Mario G. Solari, Kacey G. Marra, J. Peter Rubin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
vascularized composite allotransplantation
mesenchymal stem cell
immunomodulation
human leukocyte antigen
adipose-derived mesenchymal stem cells
bone marrow-derived mesenchymal stem cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01642/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01642/full

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