Acute erythemal ultraviolet radiation causes systemic immunosuppression in the absence of increased 25-hydroxyvitamin D3 levels in male mice.

Vitamin D is synthesised by ultraviolet (UV) irradiation of skin and is hypothesized to be a direct mediator of the immunosuppression that occurs following UV radiation (UVR) exposure. Both UVR and vitamin D drive immune responses towards tolerance by ultimately increasing the suppressive activities...

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Bibliographic Details
Main Authors: Shelley Gorman, Naomi M Scott, Daryl H W Tan, Clare E Weeden, Robert C Tuckey, Jacqueline L Bisley, Michele A Grimbaldeston, Prue H Hart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23049920/pdf/?tool=EBI