Evolution of drug resistance in HIV protease

Evolution of drug resistance in HIV protease

Abstract Background Drug resistance is a critical problem limiting effective antiviral therapy for HIV/AIDS. Computational techniques for predicting drug resistance profiles from genomic data can accelerate the appropriate choice of therapy. These techniques can also be used to identify protease mut...

Full description

Bibliographic Details
Main Authors: Dhara Shah, Christopher Freas, Irene T. Weber, Robert W. Harrison
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Bioinformatics
Subjects:
HIV protease
Drug resistance
Machine learning
Evolution
Structure-based
Online Access:https://doi.org/10.1186/s12859-020-03825-7

Internet

https://doi.org/10.1186/s12859-020-03825-7

Similar Items