Cross Modulation between the Androgen Receptor Axis and Protocadherin-PC in Mediating Neuroendocrine Transdifferentiation and Therapeutic Resistance of Prostate Cancer

Cross Modulation between the Androgen Receptor Axis and Protocadherin-PC in Mediating Neuroendocrine Transdifferentiation and Therapeutic Resistance of Prostate Cancer

Castration-resistant prostate cancers (CRPCs) that relapse after androgen deprivation therapies (ADTs) are responsible for the majority of mortalities from prostate cancer (PCa). While mechanisms enabling recurrent activity of androgen receptor (AR) are certainly involved in the development of CRPC...

Full description

Bibliographic Details
Main Authors: Stéphane Terry, Pascale Maillé, Habiba Baaddi, Laurence Kheuang, Pascale Soyeux, Nathalie Nicolaiew, Jocelyn Ceraline, Virginie Firlej, Himisha Beltran, Yves Allory, Alexandre de la Taille, Francis Vacherot
Format: Article
Language:English
Published: Elsevier 2013-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861380070X

Internet

http://www.sciencedirect.com/science/article/pii/S147655861380070X

Similar Items